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Independent impact of thrombolytic therapy and vessel patency on left ventricular dilation after myocardial infarction. Serial echocardiographic follow-up.
Author(s) -
Aleksandar D. Popović,
Aleksandar Nešković,
Rade Babić,
Velibor Obradović,
L Bozinović,
Jelena Marinković,
J C Lee,
M. Tan,
James D. Thomas
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.90.2.800
Subject(s) - medicine , timi , myocardial infarction , cardiology , thrombolysis , ejection fraction , streptokinase , infarction , end systolic volume , stroke volume , heart failure
It has been shown that successful reperfusion of the infarct-related artery by thrombolysis can prevent left ventricular dilation after acute myocardial infarction; these beneficial effects were detected from several days to several months after infarction. To date, however, no study has shown that these effects can be demonstrated within hours after the onset of infarction. Furthermore, data are scarce on the independent impact of thrombolytic therapy and late vessel patency on ventricular volume and function. The aim of this study was to assess separate effects of thrombolysis and patency of the infarct-related artery on left ventricular size and function by serial two-dimensional echocardiographic examinations.

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