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Acute vascular effects of estrogen in postmenopausal women.
Author(s) -
D. Gilligan,
D M Badar,
Julio A. Panza,
Arshed A. Quyyumi,
R O Can
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.90.2.786
Subject(s) - medicine , sodium nitroprusside , vasodilation , brachial artery , endocrinology , estrogen , forearm , endothelial dysfunction , vasomotor , endothelium , cardiology , nitric oxide , blood pressure , surgery
Although hormone replacement therapy has been associated with reduction of cardiovascular events in postmenopausal women, the mechanisms that mediate this apparent benefit are unclear. Because improvement in vasomotor function may represent one of the beneficial effects of estrogen administration, we investigated the acute effects of physiological levels of estrogen on the vascular responses of estrogen-deficient postmenopausal women.

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