Open AccessMetoprolol does not attenuate atherosclerosis in lipid-fed rabbits exposed to environmental tobacco smoke.
Author(s) -
Yongxin Sun,
Bin Zhu,
Richard E. Sievers,
Stanton A. Glantz,
William W. Parmley
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.5.2260
Subject(s) - medicine , metoprolol , tobacco smoke , pharmacology , cardiology , environmental health
We previously demonstrated that exposure to environmental tobacco smoke (ETS) increases the development of atherosclerosis in lipid-fed rabbits. Clinical studies have suggested a protective effect of beta-blockers in smokers. Accordingly, we evaluated the effects of metoprolol in this animal model to see whether this beta-blocker would block the atherogenic effects of ETS.
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