Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs.
Author(s) -
Shmuel Banai,
Michael T. Jaklitsch,
Magang Shou,
Daisy F. Lazarous,
Mickey Scheinowitz,
Sadatoshi Biro,
Stephen E. Epstein,
Ellis F. Unger
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.5.2183
Subject(s) - medicine , cardiology , blood flow , collateral circulation , vascular endothelial growth factor , collateral , vegf receptors , finance , economics
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen that is angiogenic in vitro and in vivo. It has been hypothesized that VEGF plays a role in myocardial collateral formation; however, the effects of VEGF on collateral flow to ischemic myocardium are unknown.
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