Efficient repopulation of denuded rabbit arteries with autologous genetically modified endothelial cells. | Zendy

Michael S. Conte | Zendy; Louis K. Birinyi | Zendy; Tetsuro Miyata | Zendy; John T. Fallon | Zendy; Herman K. Gold | Zendy; Anthony D. Whittemore | Zendy; Richard C. Mulligan | Zendy

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Efficient repopulation of denuded rabbit arteries with autologous genetically modified endothelial cells.

Author(s) -

Michael S. Conte,

Louis K. Birinyi,

Tetsuro Miyata,

John T. Fallon,

Herman K. Gold,

Anthony D. Whittemore,

Richard C. Mulligan

Publication year - 1994

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.89.5.2161

Subject(s) - medicine , atherectomy , staining , endothelium , pathology , balloon catheter , endothelial stem cell , cell , recombinant dna , microbiology and biotechnology , restenosis , biology , balloon , gene , in vitro , surgery , biochemistry , stent

In an effort to determine whether specific genetic modifications of cells of the vascular system might improve the efficacy of existing clinical procedures such as endarterectomy, atherectomy, and percutaneous angioplasty, we investigated the utility of gene transfer to rapidly and efficiently repopulate injured arteries with genetically modified cells in an animal model.

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