Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography. The Canadian Coronary Atherosclerosis Intervention Trial.
Author(s) -
David D. Waters,
Lyall Higginson,
Peter Gladstone,
B P Kimball,
M. Le May,
Stephen J. Boccuzzi,
Jacques Lespérance
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.3.959
Subject(s) - lovastatin , medicine , placebo , coronary atherosclerosis , hyperlipidemia , reductase , cholesterol , cardiology , hmg coa reductase , lipoprotein , gastroenterology , urology , endocrinology , coronary artery disease , pathology , diabetes mellitus , enzyme , biochemistry , chemistry , alternative medicine
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors are widely prescribed for hyperlipidemia, yet their effect on the evolution of coronary atherosclerosis has not been defined.
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