Kinetic properties of 99mTc-Q12 in canine myocardium.
Author(s) -
Myron C. Gerson,
R. W. Millard,
Nancy J. Roszell,
Anthony J. McGoron,
Marjorie Gabel,
Lee C. Washburn,
Danuta Biniakiewicz,
D’Arbra Blankenship,
W. Mallin,
R. C. Elder
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.3.1291
Subject(s) - medicine , blood flow , dipyridamole , coronary vasodilator , perfusion , circumflex , cardiology , hemodynamics , artery , coronary circulation , vasodilation , coronary occlusion , ischemia , anesthesia
99mTc-Q12 is a new Tc(III) perfusion imaging agent that permits prompt myocardial visualization in humans. We postulated that 99mTc-Q12 myocardial activity is related to actual myocardial blood flow during conditions of myocardial ischemia and pharmacological coronary artery vasodilation and that 99mTc-Q12 shows little or no myocardial redistribution as long as 4 hours after intravenous injection.
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