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Coronary flow reserve calculated from pressure measurements in humans. Validation with positron emission tomography.
Author(s) -
Bernard De Bruyne,
T. Baudhuin,
Jacques Melin,
Nico H.J. Pijls,
Stanislas U. Sys,
Anne Bol,
Walter J. Paulus,
Guy R. Heyndrickx,
William Wijns
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.3.1013
Subject(s) - medicine , fractional flow reserve , aortic pressure , cardiology , coronary flow reserve , stenosis , perfusion , cardiac catheterization , coronary circulation , vasodilation , coronary vasodilator , blood flow , hemodynamics , myocardial infarction , coronary angiography
Experimental studies have shown that fractional flow reserve (defined as the ratio of maximal achievable flow in a stenotic area to normal maximal achievable flow) can be calculated from coronary pressure measurements only. The objectives of this study were to validate fractional flow reserve calculation in humans and to compare this information with that derived from quantitative coronary angiography.

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