Native beta-adrenergic support for left ventricular dysfunction in experimental mitral regurgitation normalizes indexes of pump and contractile function. | Zendy

M Nagatsu | Zendy; Michael R. Zile | Zendy; Hiroyuki Tsutsui | Zendy; Phillip G. Schmid | Zendy; Gilberto DeFreyte | Zendy; George Cooper | Zendy; Blasé A. Carabello | Zendy

Open Access

Native beta-adrenergic support for left ventricular dysfunction in experimental mitral regurgitation normalizes indexes of pump and contractile function.

Author(s) -

M Nagatsu,

Michael R. Zile,

Hiroyuki Tsutsui,

Phillip G. Schmid,

Gilberto DeFreyte,

George Cooper,

Blasé A. Carabello

Publication year - 1994

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.89.2.818

Subject(s) - medicine , cardiology , ejection fraction , mitral regurgitation , inotrope , regurgitation (circulation) , blockade , heart failure , receptor

It is generally accepted that the adrenergic nervous system provides inotropic support for the failing heart. However, the magnitude of this support has never been studied extensively. The present study was performed to test the hypothesis that the adrenergic nervous system is capable of maintaining indexes of pump and contractile function in the normal range despite significant innate myocardial depression.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research