Relation between left ventricular oxygen consumption and pressure-volume area in conscious dogs.
Author(s) -
Takashi Nozawa,
C P Cheng,
Toshihiro Noda,
William C. Little
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.2.810
Subject(s) - dobutamine , medicine , contractility , anesthesia , cardiology , beat (acoustics) , fissipedia , phenylephrine , blood pressure , hemodynamics , physics , acoustics
The relation between left ventricular (LV) oxygen consumption (MVO2) and pressure-volume area (PVA) developed in isolated hearts provides a powerful method to understand cardiac energetics. We investigated application of this relation to the intact circulation, determining its response to steady-state and transient load alterations and enhanced contractility in conscious animals.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom