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Relation between left ventricular oxygen consumption and pressure-volume area in conscious dogs.
Author(s) -
Takashi Nozawa,
C P Cheng,
Toshihiro Noda,
William C. Little
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.2.810
Subject(s) - dobutamine , medicine , contractility , anesthesia , cardiology , beat (acoustics) , fissipedia , phenylephrine , blood pressure , hemodynamics , physics , acoustics
The relation between left ventricular (LV) oxygen consumption (MVO2) and pressure-volume area (PVA) developed in isolated hearts provides a powerful method to understand cardiac energetics. We investigated application of this relation to the intact circulation, determining its response to steady-state and transient load alterations and enhanced contractility in conscious animals.

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