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Oral verapamil inhibits platelet thrombus formation in humans.
Author(s) -
L. L-Lacoste,
Jules Y.T. Lam,
Joseph Hung,
David D. Waters
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.2.630
Subject(s) - verapamil , medicine , antithrombotic , aspirin , thrombus , platelet , thrombin , platelet aggregation inhibitor , cardiology , coronary vasodilator , pharmacology , coronary thrombosis , thrombosis , anesthesia , vasodilation , calcium
Calcium antagonists such as verapamil are potent coronary and systemic vasodilators that are used in the treatment of coronary disease. They have also been shown to inhibit platelet aggregation in vitro, but whether they have beneficial antithrombotic effects in humans is unclear, and whether they can potentiate the antithrombotic effects of aspirin is unknown.

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