Effect of calcitonin gene-related peptide on coronary microvessels and its role in acute myocardial ischemia.
Author(s) -
Nobuyo Sekiguchi,
Hiroshi Kanatsuka,
Kazutoshi Sato,
Yan Wang,
K. Akai,
Tatsuya Komaru,
T. Takishima
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.1.366
Subject(s) - calcitonin gene related peptide , medicine , dilator , cardiology , calcitonin , ischemia , vasodilation , endocrinology , artery , coronary circulation , blood flow , anesthesia , receptor , neuropeptide
Calcitonin gene-related peptide (CGRP) is a potent dilator of epicardial conduit vessels and is released during myocardial ischemia in humans. However, the effect of CGRP on coronary arterial microvessels is still unclear, and it is unknown if CGRP modulates the tone of coronary arterial microvessels during acute myocardial ischemia.
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