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Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension.
Author(s) -
B. Schwartzkopff,
W. Motz,
H. Frenzel,
M. Vogt,
Sabine Knauer,
B. E. Strauer
Publication year - 1993
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.88.3.993
Subject(s) - medicine , cardiology , coronary flow reserve , dipyridamole , vasodilation , coronary artery disease , angina , fibrosis , coronary atherosclerosis , vascular resistance , coronary arteries , fractional flow reserve , artery , hemodynamics , myocardial infarction , coronary angiography
In hypertensive patients with angina pectoris, the coronary vasodilator reserve is frequently impaired despite a normal coronary angiogram. Experimental data indicate that structural alterations of the intramyocardial coronary vasculature contribute to an increased minimal coronary resistance and a diminished coronary flow reserve.

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