Open AccessMyocardial glucose uptake in patients with insulin-dependent diabetes mellitus assessed quantitatively by dynamic positron emission tomography.
Author(s) -
Jürgen vom Dahl,
William H. Herman,
Rodney J. Hicks,
F. J. Ortiz-Alonso,
K S Lee,
Kevin C. Allman,
Edwin R. Wolfe,
Victor Kalff,
Markus Schwaiger
Publication year - 1993
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.88.2.395
Subject(s) - medicine , diabetes mellitus , positron emission tomography , insulin , glucose uptake , endocrinology , carbohydrate metabolism , glucose clamp technique , cardiology , pancreatic hormone , insulin resistance , nuclear medicine
Animal studies have demonstrated reduced myocardial glucose utilization in the diabetic heart, suggesting abnormalities in glucose transport. This study was designed to evaluate myocardial glucose uptake as assessed by 2-fluoro-(fluorine-18)2-deoxy-D-glucose (FDG) and positron emission tomography (PET) in patients with insulin-dependent diabetes mellitus (IDDM) under standardized metabolic conditions.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom