Low doses of scopolamine increase cardiac vagal tone in the acute phase of myocardial infarction. | Zendy

Barbara Casadei | Zendy; Athanase Pipilis | Zendy; Francesco Sessa | Zendy; James Conway | Zendy; Peter Sleight | Zendy

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Low doses of scopolamine increase cardiac vagal tone in the acute phase of myocardial infarction.

Author(s) -

Barbara Casadei,

Athanase Pipilis,

Francesco Sessa,

James Conway,

Peter Sleight

Publication year - 1993

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.88.2.353

Subject(s) - medicine , vagal tone , heart rate variability , baroreflex , anesthesia , myocardial infarction , placebo , cardiology , heart rate , atropine , sinus rhythm , blood pressure , atrial fibrillation , alternative medicine , pathology

Reduced cardiac vagal tone in patients with myocardial infarction (MI) is associated with a high risk of sudden death. Muscarinic blocking agents in small doses induce a paradoxical increase in cardiac vagal activity in normal subjects. We tested whether low doses of scopolamine delivered transdermally enhance tonic and reflex cardiac vagal activity in patients in the acute phase of MI.

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