Differential effects of isoproterenol on sustained ventricular tachycardia before and during procainamide and quinidine antiarrhythmic drug therapy. | Zendy

Michael L. Markel | Zendy; William M. Miles | Zendy; J. Carter Luck | Zendy; L. Klein | Zendy; Eric N. Prystowsky | Zendy

Open Access

Differential effects of isoproterenol on sustained ventricular tachycardia before and during procainamide and quinidine antiarrhythmic drug therapy.

Author(s) -

Michael L. Markel,

William M. Miles,

J. Carter Luck,

L. Klein,

Eric N. Prystowsky

Publication year - 1993

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.87.3.783

Subject(s) - medicine , procainamide , quinidine , qrs complex , cardiology , ventricular tachycardia , qt interval , anesthesia

Autonomic modulation, especially increased sympathetic activity may play a role in the genesis of ventricular arrhythmias. The purpose of this study was to determine whether beta-sympathetic stimulation with isoproterenol would alter sustained ventricular tachycardia (VT) circuits similarly during the drug-free and antiarrhythmic drug-treated states.

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