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Role of endogenous atrial natriuretic peptide in DOCA-salt hypertensive rats. Effects of a novel nonpeptide antagonist for atrial natriuretic peptide receptor.
Author(s) -
Yoko Hirata,
Hideki Matsuoka,
Emiko Suzuki,
Hiroshi Hayakawa,
T Sugimoto,
Y Matsuda,
Yoshikazu Morishita,
Kenji Kangawa,
Naoto Minamino,
H. Matsuo
Publication year - 1993
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.87.2.554
Subject(s) - medicine , atrial natriuretic peptide , antagonist , npr2 , npr1 , endogeny , endocrinology , natriuretic peptide , peptide , peptide hormone , cardiology , receptor , heart failure , biochemistry , chemistry
To explore roles of endogenous atrial natriuretic peptide (ANP) in blood pressure and volume regulation, we examined the effects of a newly developed ANP antagonist, HS-142-1 (HS) in deoxycorticosterone acetate (DOCA)-salt hypertensive rats.

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