Open AccessUncoupling of human cardiac beta-adrenoceptors during cardiopulmonary bypass with cardioplegic cardiac arrest.
Author(s) -
Dietmar Schranz,
A. Droege,
Andrea Broede,
G Brodermann,
Ellen Schäfer,
H Oelert,
OttoErich Brodde
Publication year - 1993
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.87.2.422
Subject(s) - forskolin , cyclase , adenylate kinase , medicine , cardiopulmonary bypass , iodocyanopindolol , isoprenaline , endocrinology , inotrope , desensitization (medicine) , agonist , receptor , intrinsic activity , stimulation
It is well known that during cardiopulmonary bypass (CPB) with cardioplegic cardiac arrest, catecholamines are vigorously increased. We therefore investigated whether this might cause desensitization of human cardiac beta-adrenoceptors.
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