Dipyridamole potentiates the myocardial infarct size-limiting effect of ischemic preconditioning. | Zendy

Tetsuji Miura | Zendy; Takashi Ogawa | Zendy; T Iwamoto | Zendy; Kazuaki Shimamoto | Zendy; Osamu Iimura | Zendy

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Dipyridamole potentiates the myocardial infarct size-limiting effect of ischemic preconditioning.

Author(s) -

Tetsuji Miura,

Takashi Ogawa,

T Iwamoto,

Kazuaki Shimamoto,

Osamu Iimura

Publication year - 1992

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.86.3.979

Subject(s) - dipyridamole , medicine , ischemic preconditioning , ischemia , adenosine , antagonist , anesthesia , adenosine receptor antagonist , pharmacology , cardiology , coronary occlusion , adenosine receptor , receptor , agonist

Recent studies implicated a key role for adenosine (ADO) receptor activation in the enhancement of ischemic tolerance by ischemic preconditioning. In this study, we aimed to test the hypothesis that dipyridamole, an ADO transport inhibitor, enhances the preconditioning effect.

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