Open AccessCellular mechanisms of differential action potential duration restitution in canine ventricular muscle cells during single versus double premature stimuli.
Author(s) -
Yoshinori Kobayashi,
Werner Peters,
Steven S. Khan,
William J. Mandel,
Hrayr S. Karagueuzian
Publication year - 1992
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.86.3.955
Subject(s) - restitution , medicine , isometric exercise , depolarization , cardiology , law , political science
We tested the hypothesis that action potential duration (APD) restitution of normal ventricular muscle cells is different during double premature stimuli (S3) compared with a single premature stimulus (S2). We propose a possible ionic mechanism for such a difference.
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