Are contraction and relaxation coupled in patients with and without congestive heart failure? | Zendy

Eric J. Eichhorn | Zendy; J. E. Willard | Zendy; Luis Álvarez | Zendy; A S Kim | Zendy; D.Brent Glamann | Zendy; R. Risser | Zendy; Paul Grayburn | Zendy

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Are contraction and relaxation coupled in patients with and without congestive heart failure?

Author(s) -

Eric J. Eichhorn,

J. E. Willard,

Luis Álvarez,

A S Kim,

D.Brent Glamann,

R. Risser,

Paul Grayburn

Publication year - 1992

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.85.6.2132

Subject(s) - contractility , medicine , cardiology , contraction (grammar) , afterload , heart failure , inflection point , blood pressure , mathematics , geometry

Although changes in contractility are often accompanied by changes in relaxation, a mathematical model of ventricular coupling has not been described. A model we examined suggests a hyperbolic relation between measurements of contraction and relaxation. We thus tested the hypothesis that relatively load-independent measurements of contractility (end-systolic elastance [Ees]) and relaxation (the slope of the tau-to-end-systolic pressure relation [R]) were coupled.

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