Open AccessA randomized trial of late reperfusion therapy for acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction-6 Study Group.
Author(s) -
Eric J. Topol,
Robert M. Califf,
Michel Vandormael,
Cindy L. Grines,
Barry S. George,
Mark Sanz,
T Wall,
E O’Brien,
Markus Schwaiger,
Frank V. Aguirre
Publication year - 1992
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.85.6.2090
Subject(s) - medicine , angioplasty , ejection fraction , thrombolysis , myocardial infarction , cardiology , placebo , coronary occlusion , timi , tissue plasminogen activator , reperfusion therapy , cardiac catheterization , infarction , coronary arteries , artery , heart failure , pathology , alternative medicine
Experimental and observational clinical studies of acute coronary occlusion have suggested that late reperfusion prevents infarct expansion and facilitates myocardial healing. The purpose of this trial was to assess whether infarct vessel patency could be achieved in late-entry patients and what benefit, if any, can be demonstrated.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom