Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. | Zendy

D J Beuckelmann | Zendy; Michael Näbauer | Zendy; Erland Erdmann | Zendy

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Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure.

Author(s) -

D J Beuckelmann,

Michael Näbauer,

Erland Erdmann

Publication year - 1992

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.85.3.1046

Subject(s) - myocyte , contractility , medicine , heart failure , contraction (grammar) , calcium , intracellular , diastole , cardiology , heart transplantation , cardiomyopathy , transplantation , voltage clamp , endoplasmic reticulum , patch clamp , fura 2 , endocrinology , electrophysiology , cytosol , chemistry , biology , microbiology and biotechnology , biochemistry , blood pressure , enzyme

Experiments were performed in human ventricular myocytes to investigate properties of excitation-contraction coupling in patients with terminal heart failure. Myocytes were isolated from left ventricular myocardium of patients with cardiac failure caused by dilated or ischemic cardiomyopathy undergoing transplantation. These results were compared with those obtained from cells of healthy donor hearts that for technical reasons were not suitable for transplantation.

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