Conjunctive enhancement of enzymatic thrombolysis and prevention of thrombotic reocclusion with the selective factor Xa inhibitor, tick anticoagulant peptide. Comparison to hirudin and heparin in a canine model of acute coronary artery thrombosis.
Author(s) -
Gary R. Sitko,
Denise Ramjit,
Inez I. Stabilito,
Dale Lehman,
Joseph J. Lynch,
G P Vlasuk
Publication year - 1992
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.85.2.805
Subject(s) - medicine , heparin , thrombolysis , antithrombotic , bolus (digestion) , hirudin , plasminogen activator , anesthesia , pharmacology , cardiology , platelet , thrombin , myocardial infarction
Effective thrombolytic recanalization of an occluded coronary vessel is often limited by acute thrombotic reocclusion, which has galvanized the search for effective adjunctive or conjunctive antithrombotic agents.
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