Open AccessIntravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction.
Author(s) -
J D Thornton,
G S Liu,
R A Olsson,
James M. Downey
Publication year - 1992
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.85.2.659
Subject(s) - medicine , ccpa , adenosine , adenosine receptor , cardioprotection , ischemia , agonist , anesthesia , adenosine a1 receptor , ischemic preconditioning , myocardial infarction , cardiology , pharmacology , infarction , bradycardia , receptor , heart rate , blood pressure
Recent data from this laboratory indicate that pretreatment with adenosine can protect the heart against infarction via A1-receptors, but because of systemic hypotension, adenosine had to be given into the coronary circulation.
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