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Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure.
Author(s) -
Robert Cody,
Garrie J. Haas,
Philip F. Binkley,
Quinn Capers,
Robin D. G. Kelley
Publication year - 1992
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.85.2.504
Subject(s) - medicine , vascular resistance , heart failure , endothelin 1 , cardiology , pulmonary hypertension , pulmonary wedge pressure , endothelin receptor , diastole , hemodynamics , blood pressure , cardiac index , endocrinology , cardiac output , receptor
Endothelin is a family of potent vasoconstrictor peptides of vascular endothelial origin. Although it has been proposed that the vasoconstrictor effects of endothelin are produced at the local vascular level, increased plasma concentration of endothelin has been identified in cardiovascular disorders.

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