Evidence for the association of unexplained pulmonary hypertension in children with the major histocompatibility complex. | Zendy

Robyn J. Barst | Zendy; Edith Flaster | Zendy; Aiswarya Me | Zendy; M Fotino | Zendy; Jane H. Morse | Zendy

Open Access

Evidence for the association of unexplained pulmonary hypertension in children with the major histocompatibility complex.

Author(s) -

Robyn J. Barst,

Edith Flaster,

Aiswarya Me,

M Fotino,

Jane H. Morse

Publication year - 1992

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.85.1.249

Subject(s) - medicine , pulmonary hypertension , autoantibody , human leukocyte antigen , immunology , allele , histocompatibility , gastroenterology , antigen , antibody , genetics , biology , gene

A link between primary pulmonary hypertension (PPH) and autoimmune disorders has been postulated. To investigate this relation, we performed immunofluorescent antinuclear antibody tests (ANA) and serological human leukocyte antigen (HLA)-A, B, C, DR, and DQ typing on two groups of Caucasian children with unexplained pulmonary hypertension (PHT) and their parents.

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