Cardiovascular and endocrine effects of endothelin-1 at pathophysiological and pharmacological plasma concentrations in conscious dogs.
Author(s) -
Julian Donckier,
Claude Hanet,
A Berbinschi,
Laurence Galanti,
A Robert,
Henri Van Mechelen,
H. Pouleur,
JeanMarie Ketelslegers
Publication year - 1991
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.84.6.2476
Subject(s) - medicine , pathophysiology , endothelin receptor , endocrinology , blood pressure , endothelin 1 , endothelins , atrial natriuretic peptide , endothelium , receptor
Increased plasma concentrations of endothelin-1, a potent vasoconstrictor produced by the endothelium, have been reported in various pathological conditions. This study was conducted to evaluate effects of endothelin-1 at pathophysiological and pharmacological plasma concentrations.
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