Open AccessSuppression of eicosanoid biosynthesis during coronary angioplasty by fish oil and aspirin.
Author(s) -
Gregory A. Braden,
Howard R. Knapp,
Garrett Fitzgerald
Publication year - 1991
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.84.2.679
Subject(s) - medicine , prostacyclin , platelet , fish oil , aspirin , thromboxane a2 , thromboxane , cardiology , endocrinology , eicosanoid , arachidonic acid , pharmacology , biochemistry , chemistry , biology , fish <actinopterygii> , fishery , enzyme
Percutaneous transluminal coronary angioplasty (PTCA) is an acute, localized stimulus to platelet and vascular function. Periprocedural cardiovascular complications are reduced by moderate-dose aspirin (ASA), presumably due to inhibition of thromboxane (TX) A2.