Abnormal hormonal and renal responses to saline load in hypertensive patients with parental history of cardiovascular accidents. | Zendy

Massimo Volpe | Zendy; Giuseppe Lembo | Zendy; Nicola De Luca | Zendy; F Lamenza | Zendy; C Tritto | Zendy; Bruno Ricciardelli | Zendy; Maria Cristina Molaro | Zendy; Paula Campora | Zendy; Gianluigi Condorelli | Zendy; V Rendina | Zendy

Open Access

Abnormal hormonal and renal responses to saline load in hypertensive patients with parental history of cardiovascular accidents.

Author(s) -

Massimo Volpe,

Giuseppe Lembo,

Nicola De Luca,

F Lamenza,

C Tritto,

Bruno Ricciardelli,

Maria Cristina Molaro,

Paula Campora,

Gianluigi Condorelli,

V Rendina

Publication year - 1991

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.84.1.92

Subject(s) - medicine , family history , blood pressure , plasma renin activity , endocrinology , stroke (engine) , aldosterone , renin–angiotensin system , saline , hormone , urinary system , cardiology , mechanical engineering , engineering

Acute cardiac and cerebrovascular accidents are more frequent in hypertensive subjects with a family history of acute vascular accidents. The mechanisms underlying the susceptibility to vascular disease in these subjects are unknown. We investigated whether a parental history of premature heart attack or stroke in hypertensive subjects is associated with abnormalities of sodium handling.

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