Canine myocardial creatine kinase isoenzymes after chronic coronary artery occlusion.
Author(s) -
Scott W. Sharkey,
MaryAnn M Murakami,
Stephen A. Smith,
Fred S. Apple
Publication year - 1991
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.84.1.333
Subject(s) - medicine , cardiology , occlusion , right coronary artery , coronary occlusion , artery , creatine kinase , ischemia , myocardial infarction , coronary angiography
Creatine kinase (CK) exists as three cytosolic isoenzymes, CK-MM, CK-MB, and CK-BB, and one mitochondrial isoenzyme. Animal and human observations suggest that the CK-MB content of myocardium is dynamic and may increase in response to ischemia, but the response of the myocardial CK system to chronic coronary artery occlusion is not well-defined.
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