A new method for assessment of cultured cardiac myocyte contractility detects immune factor-mediated inhibition of beta-adrenergic responses. | Zendy

T Gulick | Zendy; Stephen J. Pieper | Zendy; Moira Murphy | Zendy; L G Lange | Zendy; George F. Schreiner | Zendy

Open Access

A new method for assessment of cultured cardiac myocyte contractility detects immune factor-mediated inhibition of beta-adrenergic responses.

Author(s) -

T Gulick,

Stephen J. Pieper,

Moira Murphy,

L G Lange,

George F. Schreiner

Publication year - 1991

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.84.1.313

Subject(s) - contractility , myocyte , medicine , extracellular , immune system , cardiac myocyte , endocrinology , intracellular , cardiac function curve , adenosine , heart failure , biology , microbiology and biotechnology , immunology

Potentially reversible congestive heart failure accompanies disease states associated with an immune cell myocardial infiltrate such as cardiac allograft rejection and inflammatory myocarditis. We therefore examined the hypothesis that immune cells can produce noncytotoxic alterations in cardiac function.

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