Open AccessElectrophysiological effects of left ventricular hypertrophy. Effect of calcium and potassium channel blockade.
Author(s) -
Peter R. Kowey,
T D Friechling,
J. C. Sewter,
Ying Wu,
Alexis B. Sokil,
Jonathan Paúl,
J Nocella
Publication year - 1991
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.83.6.2067
Subject(s) - medicine , effective refractory period , refractory period , repolarization , ventricle , electrophysiology , cardiology , ventricular fibrillation , left ventricular hypertrophy , blood pressure
To define the arrhythmogenic effects of left ventricular hypertrophy (LVH) in the intact heart, we carried out a detailed electrophysiological assessment in our previously validated feline aortic-banding model and then tested the effects of agents that blocked either the slow inward calcium or voltage-dependent potassium channel.
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