Open AccessCorrelation of circulating von Willebrand factor levels with cardiovascular hemodynamics.
Author(s) -
William F. Penny,
Mark Weinstein,
E W Salzman,
J. Anthony Ware
Publication year - 1991
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.83.5.1630
Subject(s) - medicine , von willebrand factor , cardiology , platelet , vascular resistance , hemodynamics , pulmonary artery , platelet activation , cardiac catheterization , stenosis
Valvular heart disease is associated with a decreased platelet circulating time and a thrombotic tendency. The possibility that these events are related to changes in von Willebrand factor (vWF), a multimeric glycoprotein released from endothelial cells and platelets that mediates platelet adhesion to the vascular subendothelium, has not been examined.
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