Prevention of nitrate tolerance with angiotension converting enzyme inhibitors. | Zendy

Richard J. Katz | Zendy; Warren S. Levy | Zendy; Leslie A. Buff | Zendy; Alan G. Wasserman | Zendy

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Prevention of nitrate tolerance with angiotension converting enzyme inhibitors.

Author(s) -

Richard J. Katz,

Warren S. Levy,

Leslie A. Buff,

Alan G. Wasserman

Publication year - 1991

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.83.4.1271

Subject(s) - captopril , enalapril , medicine , placebo , angiotensin converting enzyme , sublingual administration , ace inhibitor , endocrinology , anesthesia , pharmacology , blood pressure , alternative medicine , pathology

Activation of neurohumoral hormones or sulfhydryl group depletion may contribute to the development of nitroglycerin tolerance. In an attempt to prevent nitrate tolerance, this study evaluated the interaction of nitroglycerin with angiotensin converting enzyme (ACE) inhibitors with and without a sulfhydryl group.

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