Open AccessA Quantitative Metabolic Defect in Lipid Metabolism Associated with Abnormal Serum Lipoproteins in Man
Author(s) -
Max W. Biggs,
D.M. Colman
Publication year - 1953
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.7.3.393
Subject(s) - lipoprotein , medicine , metabolism , lipid metabolism , cholesterol , endocrinology , blood lipids , plasma lipoprotein , biochemistry , biology
Tritium-labeled cholesterol has been fed to a selected series of patients to demonstrate a quantitative metabolic defect in lipid metabolism in the presence of abnormal serum lipoprotein spectra. Patients with abnormal serum lipoprotein spectra carry a greater fraction of their newly absorbed cholesterol in the esterified form than do normals.
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