The Effect of Posture on the Excretion of Water and Sodium by Patients with Congestive Heart Failure
Author(s) -
THOMAS A. LOMBARDO
Publication year - 1953
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.7.1.91
Subject(s) - medicine , heart failure , diuresis , excretion , sodium , cardiology , natriuresis , central venous pressure , sitting , blood pressure , endocrinology , heart rate , renal function , chemistry , organic chemistry , pathology
Four patients with congestive heart failure were studied in the sitting and the recumbent positions. After hypotonic loading maximal diuresis set in at six hours, as compared with three hours in the normal subjects. Heart failure patients never excreted more than 50 per cent of water intake in either position. Likewise, these patients never equalled sodium intake with urinary excretion of sodium. Sodium excretion in the two positions was approximately the same. Increase in venous pressure, lengthening of circulation time, decline of vital capacity, and decline of serum sodium concentration were noted after each investigation period. These results are interpreted as indicating that the previously postulated intracranial volume regulating center is either inactive or over-powered by a more powerful mechanism in the patient with congestive heart failure.
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