Side effects of long-term amiodarone therapy. | Zendy

Louise Harris | Zendy; William J. McKenna | Zendy; Edward Rowland | Zendy; David W. Holt | Zendy; G. Storey | Zendy; D M Krikler | Zendy

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Side effects of long-term amiodarone therapy.

Author(s) -

Louise Harris,

William J. McKenna,

Edward Rowland,

David W. Holt,

G. Storey,

D M Krikler

Publication year - 1983

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.67.1.45

Subject(s) - medicine , amiodarone , head and neck , dermatology , surgery , atrial fibrillation

Although amiodarone is an effective antiarrhythmic agent, long-term therapy may be associated with unwanted effects. We report our experience in 140 patients treated over 5 years. Important effects were seen particularly in the thyroid gland, liver, lung and skin. Some of these effects are dose-dependent and others may be related to the chemical structure and metabolism of amiodarone. Corneal microdeposits were always found when sought, but did not cause impairment of visual acuity.

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