Left ventricular ejection fraction calculated from volumes and areas: underestimation by area method. | Zendy

J A Wisneski | Zendy; Catherine Nina Pfeil | Zendy; D. George Wyse | Zendy; R. A. Mitchell | Zendy; S H Rahimtoola | Zendy; Edward W. Gertz | Zendy

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Left ventricular ejection fraction calculated from volumes and areas: underestimation by area method.

Author(s) -

J A Wisneski,

Catherine Nina Pfeil,

D. George Wyse,

R. A. Mitchell,

S H Rahimtoola,

Edward W. Gertz

Publication year - 1981

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.63.1.149

Subject(s) - ejection fraction , medicine , cardiology , fraction (chemistry) , stroke volume , diastole , magnification , heart failure , blood pressure , physics , chemistry , organic chemistry , optics

The ejection fraction is one of the most widely used measurements of left ventricular systolic function. Angiographic measurement of ejection fraction is based on determination of roentgenographic magnification and calculation of end-diastolic and end-systolic volumes, assuming a prolated ellipse. Because it is simple and radiographic magnification may not have been determined, some laboratories have obtained an "ejection fraction" by comparison of end-diastolic and end-systolic areas. A comparison of the two methods was made using ventriculograms of 538 patients from three cardiac catheterization laboratories. The area method of ejection fraction calculation consistently underestimates ejection fraction from left ventricular volumes. A regression equation was derived that allows adjustment of the ejection fraction obtained from areas to that from volumes.

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