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The Inhibition of Coronary Atherosclerosis by Estrogens in Cholesterol-Fed Chicks
Author(s) -
R Pick,
Jeremiah Stamler,
Simon Rodbard,
Louis N. Katz
Publication year - 1952
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.6.2.276
Subject(s) - medicine , cholesterol , estrogen , endocrinology , coronary atherosclerosis , aorta , coronary heart disease
Chronic administration of estrogens parenterally inhibits coronary atherogenesis in cockerels fed a cholesterol-supplemented diet, although no such prophylactic effect was observed against aorta atherogenesis. This protection of the coronary vessels is associated with depression of the plasma total cholesterol-lipid phosphorus ratio toward normal levels consequent upon estrogen-induced hyperphospholipemia.

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