Serum glycoproteins in coronary artery disease.
Author(s) -
S W Snyder,
Eugene L. Coodley,
Beatrice C. Durham,
Ronald S. Pennock
Publication year - 1977
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.56.3.359
Subject(s) - glycoprotein , medicine , transferrin , haptoglobin , coronary artery disease , orosomucoid , cardiology , biochemistry , biology
Serum glycoprotein levels were compared in two groups of age- and sex-matched patients, 15 with coronary artery disease and 14 normal controls. While total glycoprotein levels were increased in the coronary group, significantly higher levels were found in only five of 16 glycoproteins--C3c haptoglobin, GC-globulin, alpha1-acid glycoprotein, and C3 activator--with no change in 10 other glycoproteins and significant decrease in transferrin. This study demonstrates what appears to be a glycoprotein profile in coronary artery disease and reviews possible interactions of glycoproteins with known risk factors in atherogenesis.
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