Efficacy of oxygen enriched gas mixtures in the treatment of acute myocardial infarction.

IN THIS ISSUE, Maroko and associates report evidence, obtained from experiments in dogs, that .a well tolerated increase in the inspired concentration of oxygen (40%) reduces acute myocardial ischemic injury significantly. Differences were striking when compared to animals breathing the normal room air concentration of oxygen (21%) and studied in an otherwise identical manner. In another group of dogs, exposure to 100% 02, a level known to produce pulmonary damage if continued for long periods of time, was not associated with additional improvement