Thallium-201 for myocardial imaging. Relation of thallium-201 to regional myocardial perfusion. | Zendy

H. William Strausś | Zendy; Kimberly R. Harrison | Zendy; James Langan | Zendy; Edward A. Lebowitz | Zendy; Bertram Pitt | Zendy

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Thallium-201 for myocardial imaging. Relation of thallium-201 to regional myocardial perfusion.

Author(s) -

H. William Strausś,

Kimberly R. Harrison,

James Langan,

Edward A. Lebowitz,

Bertram Pitt

Publication year - 1975

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.51.4.641

Subject(s) - thallium , medicine , rubidium , perfusion , nuclear medicine , myocardial perfusion imaging , cardiology , blood flow , radiochemistry , potassium , chemistry , inorganic chemistry , organic chemistry

Following intravenous administration, the myocardial concentration of tracer thallium-201, potassium-43, and rubidium-81 were determined in mice; thallium was present in the greatest concentration in the myocardium (2.08% compared 1.25% for potassium and 1.15% for rubidium at 10 minutes). The regional myocardial distribution of thallium-201 was determined in dogs under conditions of normal flow, and total occlusion, and compared with potassium-43 (r=0.97). The regional distribution of thallium-201 was compared to microspheres under conditions of partial occlusion and reactive hyperemia (r=0.97). Thallium-201 was evaluated in a series of phantom scans, which demonstrated that the low energy X-ray of thallium was suitable for imaging. These results suggest that thallium-201 can be used for the evaluation of the distribution of regional myocardial perfusion.

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