Nutritional Factors in Hemodynamics
Author(s) -
Richard Lee,
Sachiko Tanaka,
Elizabeth A. Holze
Publication year - 1952
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.5.6.903
Subject(s) - medicine , blood pressure , hemodynamics , physiology , litter , folic acid , endocrinology , cardiology , biology , agronomy
Albino rats treated with pteroylglutamic acid (PGA) developed a significant increase in blood pressure, as compared with litter mate controls of the same sex. The hypertension was associated with wedge-shaped fibroblastic renal cortical lesions. Factors possibly important etiologically in the elevation of blood pressure are discussed in relation to certain of the metabolic roles of pteroylglutamic acid.
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