Changes in Exeretion of Intestinal Cholesterol and Sterol Digitonides in Hyper- and Hypothyroidism | Zendy

Meyer Friedman | Zendy; Sanford O. Byers | Zendy; Ray H. Rosenman | Zendy

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Changes in Exeretion of Intestinal Cholesterol and Sterol Digitonides in Hyper- and Hypothyroidism

Author(s) -

Meyer Friedman,

Sanford O. Byers,

Ray H. Rosenman

Publication year - 1952

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.5.5.657

Subject(s) - cholesterol , sterol , medicine , endocrinology , thyroid , excretion , digitonin , feces , biology , biochemistry , enzyme , paleontology

The fecal output of cholesterol and of noncholesterol sterols was determined in hyper- and hypo-thyroid rats, and in a group of control animals. The intestinal excretion of cholesterol and of total digitonin-precipitable sterols was found to be considerably increased in the hyperthyroid, and considerably decreased in the hypothyroid animals. The relationship of these findings to the altered plasmal cholesterol content occurring in deranged thyroid states is discussed.

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