Effect of Potassium Administration on (1) Peripheral Vascular Reactivity and (2) Blood Pressure of the Potassium-Deficient Rat | Zendy

Meyer Friedman | Zendy; Simon Freed | Zendy; Ray H. Rosenman | Zendy

Open Access

Effect of Potassium Administration on (1) Peripheral Vascular Reactivity and (2) Blood Pressure of the Potassium-Deficient Rat

Author(s) -

Meyer Friedman,

Simon Freed,

Ray H. Rosenman

Publication year - 1952

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.5.3.415

Subject(s) - potassium , medicine , blood pressure , peripheral , endocrinology , chemistry , organic chemistry

One hour after administration of potassium chloride to potassium-deficient rats, the depressed peripheral vascular response to pressor substances was significantly elevated. Administration of potassium chloride to potassium-deficient rats also returned to higher levels the lowered blood pressure of previously normotensive, as well as hypertensive rats. It appears that the depressor effect of potassium deprivation is due to the loss of peripheral vascular reactivity, both of which are rapidly restored by potassium administration specifically.

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