Open AccessComparison of the Circulatory Effects of Epinephrine and Norepinephrine
Author(s) -
Khalil G. Wakim,
Hiram E. Essex
Publication year - 1952
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.5.3.370
Subject(s) - medicine , epinephrine , circulatory system , norepinephrine , blood pressure , heart rate , anesthesia , blood flow , cardiology , dopamine
A comparison was made of the circulatory effects of l-epinephrine and l-norepinephrine when various doses were given either intravenously or intra-arterially into anesthetized animals. No significant difference was found between the effects of identical doses of the two drugs on the arterial blood pressure, heart rate and blood flow. The intensity and duration of effect of either drug varied roughly with the dose given.
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