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The Flicker Fusion Frequency and Its Response to Nitroglycerin in Normal Subjects and in Patients with Cardiovascular Disease
Author(s) -
Ancel Keys,
Ernst Simonson
Publication year - 1952
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.5.2.215
Subject(s) - medicine , flicker , disease , flicker fusion threshold , cardiology , coronary artery disease , coronary disease , coronary heart disease , electrical engineering , engineering
Krasno and Ivy have claimed that the change after sublingual nitroglycerin in the frequency at which a flickering light appears to fuse (f.f.f.) sharply differentiates between cardiovascular normals and patients with coronary and/or hypertensive disease and that this test may be useful in detecting and evaluating such disease. On the basis of a detailed analysis of the original publication and of data on 304 men these claims are denied. Indications for further study of flicker phenomena are discussed and fiducial norms are presented.

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