The Therapeutic Range of Gitalin (Amorphous) Compared with Other Digitalis Preparations | Zendy

Robert C. Batterman | Zendy; Arthur C. DeGraff | Zendy; O. Alan Rose | Zendy

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The Therapeutic Range of Gitalin (Amorphous) Compared with Other Digitalis Preparations

Author(s) -

Robert C. Batterman,

Arthur C. DeGraff,

O. Alan Rose

Publication year - 1952

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.5.2.201

Subject(s) - digitalis , digitoxin , medicine , amorphous solid , digoxin , digitalis glycosides , therapeutic index , cardiology , pharmacology , heart failure , drug , chemistry , organic chemistry

The therapeutic ranges of amorphous gitalin, digitalis leaf, digitoxin and Digoxin were compared in terms of rapid and slow methods for initial digitalization and maintenance of the digitalized patient. Gitalin (amorphous) possesses a therapeutic range greater than any available digitalis preparation or glycoside. In a group of 18 ambulatory patients, gitalin (amorphous) was found to possess an average of 41 per cent increase in therapeutic range when compared with digitalis leaf. Advantages of the use of gitalin (amorphous) as compared with other digitalis preparations are discussed.

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