Combined Papillary Muscle and Left Ventricular Wall Dysfunction as a Cause of Mitral Regurgitation | Zendy

Arun Mittal | Zendy; Manly F. Langston | Zendy; Keith Cohn | Zendy; Arthur Selzer | Zendy; William J. Kerth | Zendy

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Combined Papillary Muscle and Left Ventricular Wall Dysfunction as a Cause of Mitral Regurgitation

Author(s) -

Arun Mittal,

Manly F. Langston,

Keith Cohn,

Arthur Selzer,

William J. Kerth

Publication year - 1971

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.44.2.174

Subject(s) - medicine , papillary muscle , cardiology , mitral regurgitation , dyskinesia , infarction , mitral valve , myocardial infarction , disease , parkinson's disease

Papillary muscle infarction was produced in 16 mongrel dogs by placing sutures around the base of one of the papillary muscles. In addition, patchy infarction of the adjacent left ventricular wall was produced by placing an Ameroid constrictor around the appropriate coronary artery. Mitral insufficiency developed in 14 of these animals; it was severe in four and mild to moderate in ten. Mitral insufficiency was not produced by isolated infarction of a papillary muscle or by isolated infarction of the left ventricular wall.It is concluded that papillary muscle infarction alone does not lead to mitral regurgitation, but that papillary; muscle dysfunction acts in concert with left ventricular wall dyskinesia or dilatation to produce mitral valve incompetency.

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